Hair loss can occur due to genetics, aging, hormonal imbalances, stress, and lifestyle factors. Growth Factor Concentrate (GFC) and Platelet-Rich Plasma (PRP) therapies are advanced, non-surgical treatments designed to stimulate hair regrowth, strengthen hair follicles, and improve scalp health. Both treatments use natural growth factors from the patient’s own blood to repair damaged hair follicles, enhance blood circulation to the scalp, and promote the regrowth of thicker, healthier hair.

Growth factor therapy for hair loss uses concentrated bioactive proteins derived from platelet-rich plasma (PRP) or commercially prepared growth factor serums to stimulate dormant hair follicles and prolong the active growth phase (anagen) of the hair cycle. At Claire Derma, our dermatologists inject these growth factor preparations directly into the scalp at the level of the dermal papilla — the structure at the base of each follicle responsible for regulating hair growth.

These treatments harness the power of the body’s own growth factors and platelets to rejuvenate the scalp and stimulate hair follicles.

Growth Factor Concentrate (GFC) – A highly concentrated form of growth factors extracted from platelets, more refined than PRP, ensuring higher potency and effectiveness.

Platelet-Rich Plasma (PRP) – Derived from the patient’s own blood, processed to separate platelets and plasma to stimulate dormant hair follicles and improve density.

Rejuvenation & Blood Circulation – Both procedures increase blood supply to the scalp and prolong the hair growth cycle, leading to stronger, fuller hair.

Autologous PRP Preparation – A small blood draw is processed through dual-spin centrifugation to concentrate platelets to three to five times baseline levels.

Bioengineered Growth Factor Serums – Commercially prepared growth factor cocktails provide standardised concentrations of PDGF, VEGF, FGF, and additional peptides.

Exosome-Enhanced Preparations – Exosomes — extracellular vesicles containing growth factors, mRNA, and signalling molecules — are the newest category of growth factor delivery.

The growth factors used in hair restoration therapy each have a distinct biological function. Platelet-derived growth factor (PDGF) stimulates cell proliferation around the hair bulb. Vascular endothelial growth factor (VEGF) promotes new blood vessel formation, improving the oxygen and nutrient supply that sustaining follicles need. Fibroblast growth factor (FGF) supports the dermal papilla cells that control the hair cycle.

Hair Follicle Revitalization – Revitalizing inactive hair follicles, stimulating new hair growth.

Scalp Circulation Boost – Improving scalp blood circulation, ensuring better oxygen and nutrient supply.

Stronger Hair Growth – Strengthening existing hair, making it thicker, stronger, and less prone to breakage.

Thinning Hair Reduction – Reducing hair thinning and delaying further hair loss progression.

Dermoscopic Mapping – Before treatment, digital dermoscopy identifies zones of active miniaturisation versus complete follicular loss. This mapping directs growth factor injections to areas where viable follicles remain, avoiding treatment of spots where.

Micro-Injection Grid Pattern – Injections follow a systematic grid across the treatment zone, spaced 1cm apart for even distribution of growth factors.

Adjunct Microneedling – In some cases, microneedling at 1 to 1.5mm depth is performed immediately before growth factor application.

Growth factor therapy at Claire Derma involves a series of scalp injection sessions spaced four to six weeks apart, with a typical initial course of three to four treatments. Using fine 30-gauge needles or a mesotherapy injection device, the growth factor solution is delivered in a grid pattern across the thinning areas at a depth of 2 to 3mm.

Natural & Safe – Uses the body’s own growth factors without synthetic chemicals.

Non-Surgical Solution – No incisions or implants required, making it a minimally invasive solution.

Stimulates Natural Hair Growth – Encourages the scalp to produce stronger, healthier hair.

Increases Hair Thickness & Density – Strengthens hair shafts and reduces thinning.

Benefit – Targeted scalp delivery avoids systemic side effects. Unlike oral finasteride, which affects DHT levels body-wide, growth factor injections act locally at the follicular level.

Benefit – Stimulates natural hair biology rather than artificially propping follicles. Growth factors activate the same regenerative pathways the body uses during wound healing, reawakening dormant follicles and extending the anagen growth.

Benefit – Improvement is measurable with dermoscopy. Hair count and density metrics can be objectively recorded before and after treatment, giving both patient and dermatologist clear evidence of response.

Growth factor therapy addresses hair loss at the biological level — targeting the cellular mechanisms that control follicle activity rather than simply masking thinning. Oral medications like finasteride block DHT but carry systemic side effects. Topical minoxidil improves blood flow but requires indefinite twice-daily application.

This treatment is ideal for individuals who:

Are experiencing early to moderate hair thinning or pattern baldness.

Want to boost hair density and slow down hair loss progression.

Visible results from growth factor therapy develop over three to six months as follicles transition from dormant or miniaturised states into active growth. The first signs are typically reduced shedding — noticed around six to eight weeks after the initial session — followed by visible regrowth of finer hairs that progressively thicken.